WORKSHOP SPONSORS 2019

CAMBRIDGE PROTEIN ARRAYS

Cambridge Protein Arrays Ltd are the European distributors and service providers for HuProt™ arrays, the largest human protein arrays available, with more than 19,000 human proteins, representing more than 15,000 human genes on a single slide. HuProt™ arrays are designed for screening of antibody specificity, autoimmune profiling, and protein interactions. Cambridge Protein Arrays Ltd. is a biotech SME founded in 2010 by Mike Taussig, located in Cambridge, UK. With strong roots in the European Affinity Proteomics community, we are also the organisers of the 9th Alpbach Workshop in Affinity Proteomics.

THERMO FISHER SCIENTIFIC

Explore our extensive portfolio of more than 74,000 high-quality primary and secondary antibodies (www.Thermofisher.com/antibodies) covering over 85% of the proteome, supported by an extensive range of antibody-related products and custom services. Our antibody assays are validated by thousands of citations worldwide, helping you achieve superior results in a wide range of detection and purification applications.

QLUCORE

Qlucore  provides next-generation bioinformatic software for researchers in life science, plant and biotech industries, as well as academia, worldwide. Qlucore Omics Explorer is so easy to use that a user no longer has to depend on a bioinformatics expertise to undertake initial exploration and data analysis. The Qlucore software works with broad ranges of Omics data – Proteomics, RNA-seq, gene expression, miRNA, DNA-methylation, metabolomics, flow cytometry, clinical data etc. and differs from traditional software by giving highly interactive visualizations in both 2D and 3D. The program is lightning fast with plots and updates being presented instantaneously e.g. PCA plots, heatmaps, t-SNE and Volcano plots etc.

ABCAM

As an innovator in reagents and tools, Abcam’s purpose is to serve life science researchers globally to achieve their mission, faster. Providing the research and clinical communities with tools and scientific support, the Company offers highly validated biological binders and assays to address important targets in critical biological pathways. Already a pioneer in data sharing and ecommerce in the life sciences, Abcam’s ambition is to be the most influential company in life sciences by helping advance global understanding of biology and causes of disease, which, in turn, will drive new treatments and improved health.

THE ANTIBODY SOCIETY

The Antibody Society is an international non-profit association representing individuals and organizations involved in antibody research and development. We engage in activities that broadly benefit our members, and we encourage collaboration between companies, academia and government organizations in the antibody field. We are an authoritative source of information about antibody therapeutics development, which we disseminate via our website, presentations and publications. We also help to organize conferences on topics relevant to antibody research and development. As a global association, the Society can engage with government and international agencies such as the World Health Organization, to discuss issues of importance to the antibody community.

ATLAS ANTIBODIES

Atlas Antibodies develop, produce and market reagents for proteomic research. The products include thoroughly validated antibodies and labelled and unlabeled protein fragments for both qualitative and quantitative analysis of human proteins. The goal is to offer reagents targeting all human proteins and with more than 55,000 products, over 80% of all human proteins are currently covered. The products are marketed and sold both directly to end users worldwide and through several global and local distributors. Atlas Antibodies is a spin-out from the Swedish Human Protein Atlas (HPA) project and the majority of the research products have been developed by the HPA project for the purpose of creating a map of human protein expression and localization in normal tissues, cancers and cell lines.

IONTAS

IONTAS offers services for the discovery of antibodies using proprietary Phage Display Technology. Our services draw upon extensive experience in antibody engineering and assay development covering a wide range of targets. Each project is tailored to the specific requirements of each Partner, which facilitates delivery of project objectives in a timely manner. In addition to services, IONTAS develops phage libraries for out-licencing; and is developing other proprietary antibody discovery platforms to generate antibodies against difficult targets.

YUMAB

YUMAB’s antibody discovery technology platform provides access to human, natural, close to germline antibody candidates, with low immunogenicity, large epitope diversity, high success rates even for difficult targets like GPCRs, and pre-designed properties like interspecies cross-reactivity or specific epitope targeting. YUMAB antibodies are highly developable for all clinical indications and antibody formats, including full-length IgG and Fab, scFv, bispecifics, chimeric antigen receptors (CARs), antibody fusion proteins and conjugates (ADCs). YUMAB's portfolio covers target discovery, validation and production, personalized patient libraries, optimized antibody discovery solutions and lead development, with flexible fee-for-service solutions and collaborative partnerships.

SOMALOGIC

SomaLogic delivers meaningful and actionable health-management insights that empower individuals worldwide to continuously optimize their personal health and wellness throughout their lives. These essential insights, provided through a global network of partners and users, are derived from precise, proprietary, and personalized measurement of critical changes in an individual's proteins throughout life.

OLINK PROTEOMICS

Swedish company Olink Proteomics provides innovative solutions for targeted human protein biomarker discovery. Proseek® Multiplex enables rapid, high-throughput analysis, exceptional data quality and minimal sample consumption. Using our Proximity Extension Assay (PEA) technology, 1µl samples are analysed for 92 biomarkers simultaneously, with exceptional readout specificity. Disease-focused panels are designed together with leading experts, with full transparency on our rigorous validation data. Proseek Multiplex is available as ready-to-use kits or via our fee-for service offering.

ABSOLUTE ANTIBODY

Absolute Antibody specialises in the sequencing, engineering, and recombinant production of antibodies. We can sequence from cell lines or from purified antibody protein. Our engineering services include species/isotype switching, full humanisation, generation of custom bispecifics, and more! Our expression platform caters for milligram to gram quantities with delivery in as little as 4 weeks. All services are royalty free. We also offer a reagents catalogue that includes antibodies against common immune checkpoints, and a range of research-grade biosimilars. We're always excited to hear about new ideas and potential collaborations - ask us how we could help you at Alpbach in 2019!

CDI LABORATORIES

CDI Laboratories uses its 21,000+ human protein collection to produce HuProt™ v.4.0 - the world’s largest microarray -  containing ~87% of the proteome. CDI offers HuProt as a standalone product for labs with microarray scanning capability AND uses HuProt in its services division: ImmuneProfiler™ high-throughput biomarker discovery in autoimmune disease, oncology, predictive diagnostic assays and vaccine development. High-Spec™ antibody cross-reactivity analysis for rigorous reagent validation in grants, research and journal publications. Fast-MAb™ hybridoma and monospecific monoclonal antibody pipeline. CDI has produced more than 1500 monospecific antibodies - all tested using HuProt. CDI offers individual proteins from its library for sale in mg quantities and also specializes in antigen development.

ALLIGATOR BIOSCIENCE

Alligator Bioscience AB is a clinical-stage biotechnology company developing tumor-directed immuno-oncology antibody drugs. Alligator’s growing pipeline includes five lead clinical and preclinical drug candidates (ADC-1013, ATOR-1015, ATOR-1017, ALG.APV-527 and ATOR-1144). ADC-1013 (JNJ-7107) is licensed to Janssen Biotech, Inc., part of J&J, for global development and commercialization. Alligator’s shares are listed on Nasdaq Stockholm (ATORX). The Company is headquartered in Lund, Sweden, and has approximately 50 employees.

IMMUNOVIA

Immunovia (Lund, Sweden) is a life science company focused on developing blood based tests for cancer and autoimmune diseases. Immunovia´s core technology, IMMray™, is based on antibody biomarker microarray analysis. IMMray™ PanCan-d, now undergoing clinical validation, could be the first blood based test for early diagnosis of pancreatic cancer. The IMMray technology is generally applicable to develop solutions to unmet needs within cancer and autoimmunity. The company has started a programme focused on autoimmune diseases diagnosis, prognosis and therapy monitoring based on studies with Rheumatoid Arthritis, SLE, Vasculaitis and Sjögrens Syndrome. Additionally Immunovia has recently announced promising results within lung cancer.

CITEAB

CiteAb is a leading life science data provider that helps researchers and their suppliers make more informed decisions. Our antibody search engine provides a simple way for researchers to find antibodies that work, while our high quality market data and citations are used commercially by many of the world’s leading reagent suppliers and investment companies.

PEPPERPRINT

PEPperPRINT offers high-density peptide microarrays as well as linear and conformational epitope mapping services for antibody validation. Moreover, PEPperPRINT provides the Human Epitome Microarray with more than 23,000 human database epitopes for antibody cross-reactivity profiling and numerous other peptide microarrays for cancer, infectious disease and autoimmune research. Based on its proprietary laser-printing technology, PEPperPRINT can synthesize tens of thousands of peptides directly on the chip. The peptide microarray content can be easily customized– project by project. Recently, PEPperPRINT has broadened its product portfolio in biomarker discovery by introducing its neoepitope discovery platform for the identification of cancer biomarkers and the SeroRA® library for the development of IVD and CDx in rheumatoid arthritis.

SCIOMICS

Sciomics offers high-content analysis services for >1,000 proteins in a single assay including changes of their phosphorylation and ubiquitination status. The service is used by our customers from pharmaceutical companies and biomedical research institutes for analysis of pathway activity, elucidation of disease mechanisms, drug mode-of-action analysis, comparing different drug compounds,discovery of novel drug targets and identification and verification of protein biomarkers. The target proteins are carefully selected keyplayers in the most important biomedical pathways. Our immuno-based antibody array platform guarantees robust and reproducible results which can easily be translated into clinical assays. In addition to these CRO activities, Sciomics is active in the early-phase development of novel diagnostic means for precision medicine with a focus on cancer as well as organ failure.

SPECIFICA

Specifica specializes in delivering precisely configured, unique libraries of developable antibodies under simple, exclusive and semi-exclusive business terms. Libraries are designed to client specifications: scFv or Fab; phage or yeast; natural, synthetic or hybrid; all V genes, or a selected subset. Genetic diversity is validated by next-generation sequencing using proprietary bioinformatics protocols. Specifica also provides antibody discovery services, combining phage display, yeast display and advanced next generation sequencing and bioinformatic analysis to identify panels of antibodies with broad binding specificities, as well as the maturation of selected or client antibodies for affinity, specificity or developability.

BIO-TECHNE

Bio-Techne® unites the trusted brands: R&D Systems®, Novus Biologicals®, Tocris®, ProteinSimple® and Advanced Cell Diagnostics® (ACD). Over 250,000 products:

• Proteins and Antibodies - Validated antibodies in many formats, recombinant, natural proteins and custom services.
• Small molecules - High quality, high purity and fully annotated novel small molecules and peptides
• Protein analysis platforms - Simple PlexTM, Simple WesternTM, Single-Cell Westerns and iCETM platforms. ELISAs and Luminex® - Quantikine® and DuoSet® ELISAs, bead-based multiplex assays and Luminex® instruments.
• RNA ISH - Advanced in situ hybridization (ISH) assay RNAscope® Technology to identify target genes in any species, in any tissue.

MILTENYI

Our mission is the expansion of the frontiers of cell and gene therapy by facilitating the transition from basic research to the clinical setting. For 30 years Miltenyi Biotec has been developing products and services that are used in basic research, translational research and cell therapy. Today we are a team of more than 2,300 scientists, physicians, engineers, marketers and numerous other specialists. At Miltenyi Biotec, innovative ideas are being turned into cutting edge products. Together, we are passionate about driving biomedical progress towards curing severe diseases.

GERMAN CANCER RESEARCH CENTER

The German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) with its more than 3,000 employees is the largest biomedical research institute in Germany. At DKFZ, more than 1,200 scientists investigate how cancer develops, identify cancer risk factors and work at new strategies to prevent people from getting cancer. They develop novel approaches to make tumour diagnosis more precise and treatment of cancer patients more successful.

THE JACKSON LABORATORY

The Jackson Laboratory is a leading provider of a wide range of mouse models and services for immunology, immuno-oncology, autoimmunity, and inflammation research.   Drawing on decades of research experience, we provide capabilities around mouse model selection and husbandry to help clients and researchers evaluate novel therapies. Learn more at jax.org

ELSEVIER

Elsevier is a world-leading provider of information solutions that enhance the performance of science, health and technology professionals, empowering them to make better decisions, deliver better care, and sometimes make groundbreaking discoveries that advance the boundaries of knowledge and human progress. We provide web-based, digital solutions — among them ScienceDirect, Scopus, Evolve, Knovel, Reaxys and ClinicalKey — and publish over 2,500 journals and more than 33,000 book titles. Elsevier is part of RELX Group, a world-leading provider of information and analytics for professional and business customers across industries.

VIB CONFERENCE SERIES

VIB is a life sciences research institute in Flanders, Belgium. More than 1470 scientists from over 66 countries perform basic research into the molecular foundations of life. The institute offers a program of international VIB conferences in various VIB research fields. From day one VIB has supported and sponsored scientific conferences to help VIB scientists network with their colleagues. In 2014 the VIB Conference Series was launched to further expand these activities and support them with a dedicated professional team.