LAYOUT OF THE 2019 WORKSHOP (PRELIMINARY)
Sun 10th March: Registration, Pre-workshop Reception and Buffet Dinner at Congress Centre
DAY 1 Monday March 11th
Mike Taussig (Cambridge): Welcome and Introduction
Session 1: Protein and Cell Atlas (Chair: Mike Taussig)
- KEYNOTE: Mathias Uhlen (Stockholm)
- Kerstin Meyer (Cambridge): Towards a human cell atlas: mapping the maternal fetal interface
- Bernd Bodenmiller (Zürich): Highly multiplexed imaging of tissues with subcellular resolution by imaging mass cytometry
- Fridtjof Lund-Johansen (Oslo): Antibody array analysis meets mass spectrometry
- Dean Clift (Cambridge): Trim-Away: A new technology for direct degradation of endogenous cellular proteins
Poster Flash session I (Chair: Jochen Schwenk, Stockholm)
Session 2: Making antibodies I (Chair: John McCafferty)
- John McCafferty (Iontas)
- Michael Weiner (Abcam): Directed Targeting of Antibody Discovery
- Michael Fiebig (Absolute Antibody): From murine bispecifics to rabbit-shark fusions: New opportunities and challenges
for classic (and unusual) research reagents through protein engineering - Andrew Bradbury (Specifica): The power of next generation sequencing in antibody library generation and selection
- Thomas Schirrmann (Yumab): YUMAB - bridging innovation to drug development
- Discussion
Lunch & poster viewing
Session 3: Antibody Design and Therapeutics (Chair: Simon Goodman)
- Simon Goodman (Darmstadt): In search of the perfect beast: looking for therapeutic antibodies?
- Sarel Fleishman (Weizmann): Computational design of new and improved antibodies and binding pairs
- Björn Hock (Ferring): Engineered antibody formats and their therapeutic application
- Dario Neri (Zürich): Antibody-cytokine fusion proteins for the therapy of cancer and of chronic inflammation
- Peter Ellmark (Alligator Bio): Engineering of functional and developable TNFRSF bispecific antibodies
Session 4: Antibody Diagnostic Tools (Chair: Ulf Landegren)
- KEYNOTE: Ulf Landegren (Uppsala): Tools for high-performance protein analyses
- Carl Borrebaeck (Lund): So you think you have a proteomic test for diagnosing cancer?
- Nebojsa Janjic (SomaLogic): Nucleic acid ligands with base modification for enhanced coverage of the proteome
- Martin Lundberg (Olink)
- Jochen Schwenk (Stockholm)
Poster Flash session II (Chair: Jochen Schwenk)
Reception drinks & Poster viewing
Dinner at Congress Centre
DAY 2 Tuesday March 12th
Session 5: Nanobodies (Chair: Cecile Vincke, Brussels)
- KEYNOTE: Jan Steyaert (Brussels)
- Hidde Ploegh (Harvard): Imaging Immunity
- Ulrich Rothbauer (Tübingen): Nano- and Chromobodies: How to visualize and quantify proteins in living cells
- Markus Seeger (Zürich): Protein selections in the absence of a physical genotype-phenotype linkage
- Sophie Hernot (Brussels): Nanobodies as tracers for molecular imaging and intra-operative image-guidance
- Jim Trimmer (U.C. Davis): Recombinant antibodies and nanobodies for studying and manipulating neuronal function
- Birgit Dreier (Zurich): Binders for Challenging Tasks - A High-Throughput DARPin Selection and Validation Pipeline
Lunch, break for skiing and other activities
Session 6: Binder validation and standardisation (Chair: Matt Baker, ThermoFisher)
- Patrik Wollberg (Atlas Antibodies): Advances in Enhanced Validation ensuring reliable research results
- Alejandra Solache (Abcam):
- Industry Podium Discussion, Moderators: Matt Baker (Thermo Fisher) and Andy Chalmers (Bath): How can companies create standards for antibodies?
Dinner at Rossmoos
DAY 3 Wednesday March 13th
Session 7: Academia meets industry (Chair: Andreas Plückthun)
- KEYNOTE: Andreas Plückthun (Zurich):
- Larry Gold (SomaLogic): Large-scale proteomics for improved medicine and health
Session 8: Arrays (Chair: Peter Nilsson, Stockholm)
- Jörg Hoheisel (Heidelberg): Proteomic analyses in tumour biology: toward mechanistic insights, personalised diagnostics, and novel therapy options
- Anna Månberg (Stockholm)
- Oda Stoevesandt (Cambridge Protein Arrays): Protein arrays for validation and discovery
- Scott Paschke (CDI)
- Volker Stadler (PepperPrint)
Session 9: Making Antibodies II (Chair: Jörg Hoheisel, Heidelberg)
- Peter McPherson (McGill)
- Susanne Gräslund (Stockholm): Open-access biological probes for target validation
- Stefan Dübel (Braunschweig)
- Michael Hust (Braunschweig): Fighting pathogens and toxins with human and human-like recombinant antibodies
- Ann Holmberg (Qlucore): Instant visualisation and analysis of proteomics data
Lunch, break for skiing and other activities
Session 10: Short talks (Chair: Mike Taussig)
Mike Taussig: Winding up
Buffet Dinner and Party with Stars 'n' Bars
The mid-day break on Tuesday and Wednesday (4 hours) will allow participants to make the most of the alpine location. Dinners are open to all participants, and on Wednesday evening, we finish with our traditional party for all. This inclusive approach ensures excellent networking opportunities. See our Gallery for impressions from previous years. Biographies of Speakers and Chairs received to date can be found here.