The programme of the 2017 workshop focused on reviewing state-of-the-art technologies in Affinity Proteomics.
The 8th workshop followed the lines of our previous events to review progress in production, characterisation and application of antibodies and other binding molecules as essential tools for protein detection and analysis. The final programme is now available here.
LAYOUT OF THE 2017 WORKSHOP
Sun. 12th March: Pre-workshop Reception and Dinner
Mon. 13th March: Morning Session – Lunch break – Poster viewing – Afternoon Session – Dinner
Tue 14th & Wed. 15th March: Morning Session – Light Lunch – Mid-day Break – Coffee/Tea – Afternoon Session – Dinner
The mid-day break on Tuesday and Wednesday (4 hours) allowed participants to make the most of the alpine location. Dinners were open to all participants, and on Wednesday evening, we finished with our traditional party for all. This inclusive approach ensured excellent networking opportunities. See our Gallery for impressions from previous years.
TOPICS AND SPEAKERS
Proteome, Affinity Reagents and Mass Spectrometry
- Mathias Uhlén, SciLifeLab / Royal Institute of Technology, Stockholm, SE: Antibody-based profiling of human tissues and cells
- Kathryn Lilley, University of Cambridge, UK: Challenges in assigning the subcellular location of proteins
- John C. Rogers, Thermo Fisher Scientific, Rockford, IL, USA: Verification of antibody performance by protein IP and MS identifies antibody targets and enriches interacting proteins
- Fridtjof Lund-Johansen, Oslo University Hospital, NO: MAP-MS: A unified platform for antibody- and MS-based proteomics
- Susanne Gräslund, Karolinska Institutet, Stockholm, SE: Generation and IP-MS validation of open-access recombinant antibodies to SGC target proteins
Protein Detection with Antibodies
- Ulf Landegren, Uppsala University, SE: Tools for analysing more or less proteins
- Martin Lundberg, Olink, Uppsala, SE: Using proximity extension assay (PEA) for discovery, verification and validation studies
- Heng Zhu, Johns Hopkins Medicine, Baltimore, MD, USA: Generation of mono-specific monoclonal antibodies against human transcription factors
- Peter Nilsson, SciLifeLab / Royal Institute of Technology, Stockholm, SE: Protein array enabled profiling of autoantibody repertoires within health and disease
- Jochen Schwenk, SciLifeLab / Royal Institute of Technology, Stockholm, SE: Affinity-based Assays for Translational Proteomics
- H. Tom Soh, Stanford University, CA, USA: Real-time biosensors for continuously measuring specific biomolecules in live animals
- David Juncker, McGill University, Montreal, CA: New technologies for protein and aptamer analysis
Binder Production Technologies
- John McCafferty, Iontas, Cambridge UK: Generating ion channel blocking antibodies by fusing cysteine-knot miniproteins into peripheral CDR loops
- Michael Weiner, Abcam / AxioMx, Branford, CT, USA: Applying in vivo-based molecular biological technologies and genetics to generate IgG molecules
- Andreas Plückthun, University of Zürich, CH: Unconventional approaches to generate specific binding molecules
- Andrew Bradbury, Los Alamos National Laboratory, NM, USA: How big are antibody libraries really? And how effectively do we sample them?
Binder Validation and Standardisation
- James Trimmer, UC Davis, CA, USA: Antibody generation for neuroscience research: challenges, opportunities and lessons
- Alejandra Solache, Abcam, Cambridge, UK: Constantly Evolving and Raising Antibody Validation Standards
- Gordon Whiteley, National Cancer Institute, NIH, Bethesda, MD, USA: Fit for purpose antibodies: Making antibodies with intended use in mind
- Janice Reichert, The Antibody Society, Framingham, MA, USA
- Panel Discussion on Validation and Standardisation
Industry and Biomarkers
- Hanno Langen, Roche Innovation Center, Basel, CH: Application of Proteomics Technologies in the Pharmaceutical Industry
- Jonathan Milner, Abcam, Cambridge, UK: Serendipity and its role in biomarker discovery
Disease-related Binder Applications
- Jörg Hoheisel, German Cancer Research Center, Heidelberg, DE: Mapping the molecular communication within pancreatic cancer tumour microenvironment and between tumour and peritumoral tissue
- Stefan Dübel, Technische Universität Braunschweig, DE: Targeting the inside from the outside: new therapeutic concepts with human antibodies
- Carl Borrebaeck, Lund University, SE: Precision Diagnostics - a prerequisite for Precision Medicine in complex disease
- Karl-Friedrich Becker, Technical University of Munich, DE: Using clinical tissue samples for reverse phase protein arrays